Platform

One layer that reads what your systems hold separately.

Your QMS, LIMS, validation and submission systems each hold part of the regulatory evidence. Clinplex reads across all of them — read-only — and returns clause-cited findings, ranked by enforcement risk, with the remediation drafted. Here is the whole sequence, on real product screens.

How it works

Six steps, in sequence.

01 · CONNECT

Connect, read-only.

Records arrive by direct upload, secure export, or read-only connectors that pull from your systems on a schedule. Nothing is ever written back; your validated state is not changed by using Clinplex.

Clinplex integrations screen showing connected source systems
02 · SCAN

Scan the whole corpus, continuously.

Every record is mapped to the regulatory frameworks that govern it and evaluated in context — the SOP against its deviations, the CAPA against its commitments, the validation package against the process it validates. The dashboard shows compliance posture across the full document set, not one file at a time.

Clinplex dashboard with overall compliance status across the document corpus
03 · FINDING

Findings, with the clause attached.

Each gap arrives with seven fields: source record, governing requirement, deficiency, linked-record impact, severity, rationale and drafted remediation.

Gap Intelligence dashboard listing clause-cited gaps within an SOP
04 · CASCADE

Trace the cascade.

A gap in one record rarely stays in one record. Clinplex follows the links — the CAPAs, change controls and training records that cite the affected document — and shows the full blast radius before you change anything.

Operational Intelligence view tracing linked-record impact
05 · CAPA

Remediation, drafted and owned.

Every finding carries a drafted remediation, and the workload view shows how open findings distribute across owners and due dates — so the output lands as assignable work, not a report to re-type.

CAPA workload distribution across owners
06 · DOSSIER

The evidence dossier.

Findings, citations, severity rationale and resolution history assemble into an inspection-ready evidence trail. Because the layer runs continuously — not just before an inspection — readiness is a standing state you can show, at any inflection point of the program.

Clinplex knowledge base assembling the evidence trail
The four pillars

What the layer is made of.

Pillar 1

Gap intelligence

Cross-record, multi-framework gap detection. Records are evaluated as evidence chains — a deviation with its CAPA and governing SOP — against every framework that applies, surfacing the gaps single-framework review misses.

Pillar 2

Operational intelligence

The linked-record graph: which documents cite which, where a change cascades, which records an open finding touches. This is what turns a finding into scoped, assignable work.

Pillar 3

Regulatory intelligence

A curated mapping of the frameworks themselves — FDA, EMA, MHRA, PMDA, ICH and EU GMP — and how guidance changes ripple into your document set.

Pillar 4

Risk prioritization from enforcement patterns

Findings ranked against published enforcement history — 483 observations, warning letters, inspection outcomes — so attention goes where observations actually happen. Severity itself is set by a deterministic rules table.

Governance

How the intelligence is governed.

Outputs that feed regulated decisions need more than accuracy claims. This is the control structure around every finding.

Framework curation
The regulatory framework library is curated and maintained by the Clinplex team and updated as guidance changes. Every finding cites the specific clause it was evaluated against, so the basis of a finding is always inspectable.
Traceability
Each finding is bound to its source record, governing requirement and linked records, timestamped and attributed in an append-only, hash-chained audit trail.
Human review
Model output is advisory. A human reviews every finding; the model never sets final compliance, gap or CAPA status.
Deterministic severity
Severity comes from a rules table, not model judgment — identical evidence always yields identical severity, and the rules are reviewable.
Accuracy monitoring
Detection accuracy, false positives and false negatives are measured against a blinded SME panel. Methodology, confidence intervals and results are published on the Proof page.
Your validation process
Clinplex is read-only and not a system of record, so your validated state is unchanged. A validation documentation set and the 21 CFR Part 11 control mapping are available under NDA — see Security and trust.
Coverage

What it reads.

Document types

SOPsDeviationsCAPAsChange controlsBatch recordsAudit recordsIQ / OQ / PQ validation packagesCMC submissionsPreclinical study reportsTraining recordsSubmission modules

49 document types across the regulated set. The evaluated corpus behind that number is documented on the Proof page.

Lifecycle phases

Discovery & preclinicalQuality / manufacturingClinical operationsCMC / regulatory submissions

Four phases, with phase-aware framework mapping — the requirements applied to a record depend on where the program is.

Building next

On the bench, honestly labeled.

These are in development or research, not shipping. They're here because buyers should see where the layer is going — and hold us to the same claim discipline when they arrive.

Regulator-divergence view In development
Where the same obligation is read differently across authorities, the finding will say so — "acceptable to FDA, a finding under EU Annex 11." Scoped first to two regulators and one framework family, because a wrong divergence call is worse than none. Built on the clause-cited framework mapping that exists today.
Exposure findings Research
Text that is compliant but invites a follow-up question when read out of context by an inspector — a different detection class from non-compliance. Being prototyped against the evaluation corpus; it ships when it benchmarks, not before.
Production accuracy monitoring In development
Today, false positives and negatives are benchmarked offline against the blinded SME gold set. Continuous monitoring extends that into production, so accuracy is a live measured number rather than a study result.
Framework currency verification In development
The framework corpus is hashed and version-manifested today. Hardening the currency pipeline — proving each clause reflects the regulation as it stands — is in progress before "version-controlled and current" appears as an enterprise claim.

See it on your own records.

Send a closed deviation, its CAPA and the governing SOP. Mutual NDA goes out the same day; findings come back within 48 hours. Redacted records are fine.

Run a 3-record Inspection Stress Test