Platform

One layer that reads what your systems hold separately.

Your QMS, LIMS, validation and submission systems each hold part of the regulatory evidence. Clinplex reads across all of them — read-only — and returns clause-cited findings, ranked by enforcement risk, with the remediation drafted. Here is the whole sequence, on real product screens.

How it works

Six steps, in sequence.

01 · CONNECT

Connect, read-only.

Records arrive by direct upload, secure export, or read-only connectors that pull from your systems on a schedule. Nothing is ever written back; your validated state is not changed by using Clinplex.

Clinplex integrations screen showing connected source systems
02 · SCAN

Scan the whole corpus, continuously.

Every record is mapped to the regulatory frameworks that govern it and evaluated in context — the SOP against its deviations, the CAPA against its commitments, the validation package against the process it validates. The dashboard shows compliance posture across the full document set, not one file at a time.

Clinplex dashboard with overall compliance status across the document corpus
03 · FINDING

Findings, with the clause attached.

Each gap arrives as a structured, reviewable finding tying the source evidence to the governing requirement, impact, severity rationale and proposed remediation.

Gap Intelligence dashboard listing clause-cited gaps within an SOP
04 · CASCADE

Trace the cascade.

A gap in one record rarely stays in one record. Clinplex follows the links — the CAPAs, change controls and training records that cite the affected document — and shows the full blast radius before you change anything.

Operational Intelligence view tracing linked-record impact
05 · CAPA

Remediation, drafted and owned.

Every finding carries a drafted remediation, and the workload view shows how open findings distribute across owners and due dates — so the output lands as assignable work, not a report to re-type.

CAPA workload distribution across owners
06 · DOSSIER

The evidence dossier.

Findings, citations, severity rationale and resolution history assemble into an inspection-ready evidence trail. Because the layer runs continuously — not just before an inspection — readiness is a standing state you can show, at any inflection point of the program.

Clinplex knowledge base assembling the evidence trail
The four pillars

What the layer is made of.

Pillar 1

Gap intelligence

Cross-record, multi-framework gap detection. Records are evaluated as evidence chains — a deviation with its CAPA and governing SOP — against every framework that applies, surfacing the gaps single-framework review misses.

Pillar 2

Operational intelligence

Cross-record context shows which evidence is affected by a finding and where remediation may have downstream impact. This is what turns a finding into scoped, assignable work.

Pillar 3

Regulatory intelligence

A curated mapping of the frameworks themselves — FDA, EMA, MHRA, PMDA, ICH and EU GMP — and how guidance changes ripple into your document set.

Pillar 4

Risk prioritization from enforcement patterns

Findings are prioritized using published enforcement history so teams can focus attention on the issues most relevant to regulatory exposure. Severity is governed through a reproducible policy layer rather than free-form model judgment.

Governance

How the intelligence is governed.

Outputs that feed regulated decisions need more than accuracy claims. This is the control structure around every finding.

Framework curation
The regulatory framework library is curated and maintained by the Clinplex team and updated as guidance changes. Every finding cites the specific clause it was evaluated against, so the basis of a finding is always inspectable.
Traceability
Each finding is bound to its source record, governing requirement and linked records, captured in a timestamped, attributable, tamper-evident audit trail.
Human review
Model output is advisory. A human reviews every finding; the model never sets final compliance, gap or CAPA status.
Deterministic severity
Severity is assigned through a governed, reproducible policy layer independent of free-form model judgment, with a reviewable basis for each call.
Accuracy monitoring
Detection accuracy, false positives and false negatives are measured against a blinded SME panel. Methodology, confidence intervals and results are published on the Proof page.
Your validation process
Clinplex is read-only and not a system of record, so your validated state is unchanged. A validation documentation set and the 21 CFR Part 11 control mapping are available under NDA — see Security and trust.
Coverage

What it reads.

Document types

SOPsDeviationsCAPAsChange controlsBatch recordsAudit recordsIQ / OQ / PQ validation packagesCMC submissionsPreclinical study reportsTraining recordsSubmission modules

Broad coverage across regulated document types. The evaluated corpus behind that number is documented on the Proof page.

Lifecycle phases

Discovery & preclinicalQuality / manufacturingClinical operationsCMC / regulatory submissions

Four phases, with phase-aware framework mapping — the requirements applied to a record depend on where the program is.

Building next

On the bench, honestly labeled.

These are in development or research, not shipping. They're here because buyers should see where the layer is going — and hold us to the same claim discipline when they arrive.

Regulator-divergence view In development
Jurisdiction-aware comparison of the same evidence across authorities. This capability remains in development and will be released only after it meets Clinplex evaluation and review standards.

See it on your own records.

Send a closed deviation, its CAPA and the governing SOP. Mutual NDA goes out the same day; findings come back within 48 hours. Redacted records are fine.

Run a 3-record Inspection Stress Test